This Rune Trial can be found near the beginning of the Argent Energy Tower mission. You need to destroy 30 barrels before the time expires to unlock the Dazed and Confused Rune – increases duration of stagger state. Go to the gate marked 1 and then jump up to the right for this Rune Trial. Go inside the garage and look to your left. Don’t go down there, just head further down the walkway and you’ll see a small door. Run past the nest and you’ll see a large crate hanging down. Progress through the level until you reach one of the nests above the area with the blue forcefield, it’s quite late in the level so you can’t get there the first time you see the forcefield area. The second Rune Trial can be found on the Argent Facility mission also. This unlocks the Vacuum Rune that increases the distance in which you can grab collectibles.
It’s easy, just remember to Glory Kill whenever possible as this adds the most additional time per kill. It’s impossible to miss as it acts as an introductory challenge for the Runes feature. The first Rune Trial in Doom can be found on the Argent Facility mission when you’re trying to disable the Argent Filters.